90-Day Glaucoma: A Rare Case Report

Neovascular glaucoma (NVG) also called as 90-day glaucoma, is a potentially devastating sequela of seriousunderlying ocular and/or systemic diseases. Anterior segment neovascularization involving the iris, the angle orboth is accompanied by the formation of a fibrovascular membrane that obstructs the aqueous outflow throughthe trabecular meshwork and results in rise of IOP. Here we present a case of a fifty seven year old male whopresented with diminution of vision in left eye since 45 days associated with pain and redness L/E since 15 days.On examination visual acquity of R/E was 6/6,N6 and in L/E patient denied perception of light. Our case presentedwith almost all features suggestive of NVG except that of rubeosis iridis which makes it unique, as to the best ofour knowledge this has been very rarely reported anywhere in literature before.

Association between C-reactive protein and age-related macular degeneration

Background: Age-related macular degeneration (AMD) is the leading cause of irreversible visual impairment among the elderly, worldwide affecting 30-50 million individuals. Inflammation is now increasingly thought to be a key risk factor for AMD. The association of CRP with AMD has been reported in only a few studies, with somewhat inconsistent results. The present study was undertaken to determine the association between AMD and serum CRP levels.Methods: A total of 53 patients diagnosed of any form of AMD fulfilling inclusion and exclusion criteria were included. A 5 mL sample of venous blood (non-fasting) was collected to determine serum high-sensitivity CRP levels (hsCRP). Different stages of AMD and serum hs CRP level were compared using one-way ANOVA test and calculated p value <0.05 was considered as statistically significant. Comparison between the two groups, one with risk factor and one without risk factor was performed using student-t test and calculated p value <0.05 was considered statistically significant.Results: Out of 53 patients 21 were having early AMD, 21 were having intermediate AMD and 11 were having advanced AMD. The mean serum hs CRP level was 0.14±0.05 mg/dL, 0.20±0.09 mg/dL and 0.28±0.08 mg/dL in early, intermediate and advanced AMD respectively. When statistically analysed the difference of mean serum hs CRP level among the three groups was found to be statistically significant.Conclusions: Type of AMD influence the baseline hsCRP level. Smoking and diabetes are associated with higher baseline serum hsCRP in all stages of AMD.